1. Mechanism of action

1. Acts on the 50S subunit of bacterial ribosomes, affecting protein synthesis.

2. Mainly against Gram-positive bacteria, mycoplasma and spirochetes.

3. The antibacterial spectrum is similar to that of macrolide antibiotics.

4. It is not easy to develop drug resistance.

2. Antibacterial spectrum

It is effective against the following pathogenic microorganisms

3. Product features

1. Fast absorption and wide distribution: rapid absorption after oral administration, blood concentration reaches 1-1.5 hours peak. The concentration distributed in tissues in the body can be several times higher than the blood concentration.

2. It has strong permeability. After oral administration, it can enter the placenta, pass through the placental barrier, and can also be distributed in breast milk.

3. Strong antibacterial effect and long duration: The antibacterial effect of this product is 8-16 times that of ordinary lincomycin, and it can maintain effective blood concentration for 24 hours.

IV. Indications

1. For streptococcosis, asthma, actinomycetosis, Haemophilus parasuis, pasteurellosis, atrophic rhinitis, Proliferative enteritis, swine dysentery and various bacterial infections secondary to viral diseases, etc.

2. Used for mastitis caused by sensitive bacteria such as Escherichia coli and vertical infection between mother and child.

3. Used for sepsis, osteomyelitis, cellulitis, septic arthritis and mastitis caused by sensitive bacteria

4. Used for the prevention and treatment of chronic respiratory diseases in poultry , necrotizing enteritis, etc., as well as various respiratory diseases secondary to a variety of viruses.

5. The combined use of this product and spectinomycin is more effective in treating Mycoplasma septicarum and Escherichia coli infections in livestock and poultry.

5. Usage and dosage

1. Used for antibacterial and growth promotion:

Pigs: Add 0.4kg-0.7kg of this product per 1000kg of feed and use for 1-3 weeks.

Poultry: Add 0.02kg-0.04kg of this product to every 1000kg of feed and use for 1-3 weeks.

2. When used for health care and treatment, pigs: add 1kg of this product for every 1000kg of feed.

6. Clinical application in pig farms

(1) Peripartum health care of sows

1. Pig postpartum triad

Porcine mastitis-metritis-agalactia syndrome (MMA),

2. Common bacterial infection + stress = PPDS

Gram-positive bacteria (Streptococcus, Staphylococcus aureus), anaerobic bacteria, and certain mycoplasmas play an important role in the pathogenesis.

(2) Health care of growing and fattening pigs

1. Asthma disease

2. Streptococcus, swine erysipelas and other bacteria

3. Intestinal diseases: swine dysentery, ileitis

4. Growth promotion

7. Practical clinical application plan for pig farms

1. Mu Yikang prevents sows Plan for postpartum triad

(1) Medication plan: Add the following drugs per ton of feed

Spiron Lincomycin Soluble Powder 500g

Meiyi 1kg

(2) Medication timing:

Plan ①, use for 10 days before and after giving birth to sows.

Plan ②: Add lactating sow feed for 5-7 days every month.

(3) Effect:

Reduce the occurrence of agalactia in sows;

Reduce piglet diarrhea and significantly improve piglet survival rate;

2. Health care plan for growing and fattening pigs

(1) Pulse administration: once at 8-10 weeks of age and once at 14-16 weeks of age.

(2) Add 1000g of "Spiron Lincomycin Soluble Powder" per ton of feed, and administer it continuously for 7-10 days each time.