Chapter 1 Modern Sub-Healthy Dogs

We support a minimally processed, fresh, and rich diet, but even replacing 10% of a dog’s daily dog ​​food with fresh food will be harmful to the dog’s body. Make a positive impact.

The same factors that affect human lifespan also affect dogs: lack of variety, minimally processed diet; overeating; sedentary periods; chemical toxins in the environment; chronic stress (dogs suffer our pressure).

Chapter 2: Evolve with dogs

Many genetic diseases are the result of ancient genetic mutations and are widespread in all dog breeds, but some genetic diseases increase in frequency with inbreeding of breeds of dogs, but manifest at different levels in different dog breeds. If genetic testing reveals that a dog has some predisposing DNA mutation, a therapeutic nutritional and lifestyle program can be initiated preemptively to affect the expression of the gene.

Food not only provides energy, but also sends signals to our DNA. These signals have the ability to influence our genes, behavior, and DNA expression. These changes caused by external influences are called "epigenetics."

A pro-inflammatory diet rich in refined carbohydrates reduces the activity of important genes associated with brain health, called "epigenetics." Brain-derived neurotrophic factor, or BDNF. The gene codes for a protein, also known as BDNF, that is responsible for the growth and nutrition of brain cells. BDNF cannot be obtained from food, but there are things we can do to make a dog's body produce it as it ages. The right foods can support the body’s own ability to produce BDNF. Exercise increases the production of BDNF. Stress levels and sleep factors also affect BDNF production; in fact, reduced BDNF levels are now linked to insomnia, and research suggests this may be a vicious cycle in which high stress levels inhibit BDNF production, thereby disrupting good sleep. Research further shows that people with cognitive decline and neurodegenerative diseases have lower BDNF, while those who maintain high levels continue to improve their learning and memory while avoiding brain disease.

Chapter 3 The Science of Aging

Factors affecting epigene expression:

Nutrient levels in food Nutrient levels in food

Polyphenol levels in food Polyphenol content in food

Chemicals in food Chemicals in food

Physical activity Physical activity

Stress Stress

Obesity

Pesticides

Metals

Endocrine-disrupting chemicals

Particulate matter (secondhand smoke) particulate matter (second-hand smoke)

Air pollutants Air pollutants

Chapter 4 Fighting Aging through Diet

Dietary best practices are summarized in two Ts: Type and Timing

Type: What types of nutrients are ideal? 50/50 Protein and Fat

Given a choice, dogs will choose calories from fat and protein first and carbohydrates last. This is why many formulators recommend that approximately 50% of calories (not the volume of food) should come from protein and 50% from fat

A raw diet puts less stress on the metabolism than a kibble-fed dog, Have lower levels of inflammation and disease markers, including homocysteine ​​levels.

Starch: Chronic, low-grade inflammation is the beginning of most diseases. Inflammation is caused in part by pro-inflammatory foods, especially sugars found in refined carbohydrates.

Too much starch in pet food can cause persistent increases in blood sugar levels, which itself can create a pro-inflammatory state.

Corn, wheat, rice, potatoes, cassava, oats, lentils, chickpeas, barley, quinoa and other carbohydrates found in pet foods also promote the internal production of AGEs in the body, stimulating permanent Sexual and progressive systemic inflammation. Just like athletes have much lower resting heart rates than the average person, dogs eating a raw diet have much lower fasting blood sugar levels than dogs eating kibble. Keeping insulin and glucose levels low and stable in the body is good for the dog and is less metabolically stressful for the dog.

Fat: There are good and bad fats. Bad fats like saturated fats or trans fats can trigger inflammation and are often found in highly processed foods. Healthy fats are monounsaturated and polyunsaturated fats, which are rich in anti-inflammatory omega fatty acids. Sources of healthy fats include nuts, seeds, avocados, eggs, cold-water fatty fish like salmon and herring, and extra virgin olive oil. Fats should be unrefined, unheated and raw, heated fats produce ALE (the lipid version of AGEs).

The connection between food and microbes

Microorganisms help digest food and absorb nutrients, supporting the immune system (in fact, 70 to 80 percent of the immune system is located within the intestinal wall) , produces and releases enzymes that protect against other disease-causing bacteria; helps regulate the body's inflammatory pathways, which in turn affects the risk of almost all chronic diseases, handles stress through its effects on the hormonal system, and can even ensure a good night's sleep. The synthesis of some key vitamins, fatty acids, amino acids and neurotransmitters is also carried out by microorganisms.

Bacteria in the gut produce vitamin B12, thiamine and riboflavin, as well as vitamin K, which is needed for blood clotting. Good bacteria also reduce stress by shutting down cortisol and adrenaline. In the realm of neurotransmitters, gut bacteria play an important role in providing serotonin, dopamine, norepinephrine, acetylcholine, and gamma-aminobutyric acid.

Having a diverse colony is key to good health, and this diversity depends on dietary choices that feed the microbes and set the stage for whether the microbiome is functioning properly.

Exposure to environmental chemicals, fertilizers, contaminated water, artificial sugars, antibiotics, NSAIDs, emotional stress, trauma (including surgery), gastrointestinal disease, nutritional deficiencies, or lack of A healthy microbiome can be affected by a proper diet (metabolically stressful foods).